BCMA and Autoantibody-producing RP105 B cells ; Possible new targets of B cell therapy in systemic lupus erythematosus

Author:

KOARADA Syuichi1,TASHIRO Satoko1,SUEMATSU Rie1,INOUE Hisako1,OHTA Akihide1,TADA Yoshifumi1

Affiliation:

1. Division of Rheumatology, Saga University

Publisher

Japan Society for Clinical Immunology

Subject

General Medicine,Immunology,Immunology and Allergy

Reference20 articles.

1. 1) Miyake K, Yamashita Y, Ogata M, Sudo T, Kimoto M. : RP105, a novel B cell surface molecule implicated in B cell activation, is a member of the leucine-rich repeat protein family. J Immunol. 154 : 3333-3340, 1995.

2. Murine B cell proliferation and protection from apoptosis with an antibody against a 105-kD molecule: unresponsiveness of X-linked immunodeficient B cells.

3. RP105 Facilitates Macrophage Activation by Mycobacterium tuberculosis Lipoproteins

4. 4) Tada Y, Koarada S, Morito F, Mitamura M, Inoue H, Suematsu R, Ohta A, Miyake K, Nagasawa K. : Toll-like receptor homolog RP105 modulates the antigen-presenting cell function and regulates the development of collagen-induced arthritis. Arthritis Res Ther. 10 : R121, 2008. [Epub 2008 Oct 11]

5. B cells lacking RP105, a novel B cell antigen, in systemic lupus erythematosus

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