The possible curative therapy for rheumatoid arthritis—EBV infection control gene SAP and its application

Author:

TAKEI Masami1,KITAMURA Noboru1,SHIRAIWA Hidetaka1,INOMATA Hiromu1,NOZAKI Takamasa1,KUWANA Yosikazu1,SHIOZAKI Masaaki1,SAWADA Shigemasa1,ISHIWATA Tetsuyoshi2

Affiliation:

1. Division of Hematology and Rheumatology Department of Medicine, Nihon University School of Medicine

2. Kyowa Hakko Chemical Co., LTD Tokyo Research Laboratories

Publisher

Japan Society for Clinical Immunology

Subject

General Medicine,Immunology,Immunology and Allergy

Reference54 articles.

1. 1) Alspaugh, M.A. et al. : Lymphocyte transformed by Epstein-Barr virus : induction of nuclear antigen reactive with antibody in rheumatoid arthritis. J Exp Med, 147 : 1018-1027, 1978.

2. 2) Anzilotti C. et al. : Antibodies to viral citrullinated peptide in rheumatoid arthritis. J Rheumatol, 33 : 647-51. 2006.

3. 3) Billings, P.B. et al. : Antibodies to the Epstein-Barr virus nuclear antigen and to rheumatoid arthritis nuclear antigen identify the same polypeptide. Proc Natl Acad Sci, 80 : 7104-7108, 1983.

4. 4) Rhodes, G. et al. : Human immune response to synthetic peptides from the Epstein-Barr virus nuclear antigen. J Immunol, 134 : 211-216, 1985.

5. 5) Rumpold, H. et al. : The glycine-alanine repeating region is the major epitope of the Epstein-Barr nuclear antigen-1 (EBNA-1). J Immunol, 138 : 593-599, 1987.

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