The formation of skin barrier and defective barrier-associated skin diseases

Author:

ISHITSUKA Yosuke1

Affiliation:

1. Department of Dermatology, Faculty of Medicine, University of Tsukuba

Publisher

Japan Society for Clinical Immunology

Subject

General Medicine,Immunology,Immunology and Allergy

Reference82 articles.

1. 1) Proksch, E., et al.: The skin: an indispensable barrier. Exp Dermatol. 17: 1063-1072, 2008.

2. 2) Streilein, J.W.: Skin-associated lymphoid tissues (SALT): origins and functions. J Invest Dermatol. 80 Suppl: 12s-16s, 1983.

3. 3) Barker, J.N., et al.: Keratinocytes as initiators of inflammation. Lancet. 337: 211-214, 1991.

4. 4) Guttman-Yassky, E., et al.: Contrasting pathogenesis of atopic dermatitis and psoriasis–part I: clinical and pathologic concepts. J Allergy Clin Immunol. 127: 1110-1118, 2011.

5. 5) Palmer, C.N., et al.: Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis. Nat Genet. 38: 441-446, 2006.

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