Author:
Xiao Ying,Gao Lu,Shen Li,Yang Chenhao
Abstract
Purpose:
To investigate the correlation between demodicosis and pediatric chalazia.
Methods:
A case-control prospective study was conducted at Children's Hospital of Fudan University between December 2018 and January 2019. One hundred one consecutive pediatric patients with chalazia and 42 pediatric patients without chalazia underwent eyelash sampling and
Demodex
examination using light microscopy, and mite presence and count were documented.
Results:
The
Demodex
count and prevalence of the chalazia group was much higher than that of the control group (3.06 ± 3.48 vs 0.64 ± 1.17;
P
≤ .001; 73.3% vs 35.7%,
P
≤ .001). The
Demodex
count and prevalence of the multiple chalazia subgroup was much higher than that of the single chalazion subgroup (3.49 ± 3.72 vs 2.00 ± 2.52;
P
= .043; 79.2% vs 58.6%,
P
= .035). The
Demodex
count and prevalence of the chalazia with skin erosion subgroup was much higher than that of the without skin erosion subgroup (3.54 ± 3.14 vs 2.55 ± 3.76;
P
= .012; 82.7% vs 63.3%,
P
= .027). After adjustment for age and gender,
Demodex
count (odds ratio: 1.873; 95% confidence interval: 1.155 to 3.040;
P
= .011) but not presence (
P
= .643) was significantly correlated with chalazia.
Conclusions:
Demodex
mites were more prevalent and quantitative in children with chalazia, and children with severe chalazia had higher
Demodex
prevalence and quantity. High
Demodex
count rather than presence of it was associated with chalazia.
[
J Pediatr Ophthalmol Strabismus
. 20XX;X(X):XX–XX.]
Subject
Ophthalmology,General Medicine,Pediatrics, Perinatology and Child Health
Cited by
2 articles.
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