Author:
Lee Jessica,Chua Michael,Jansen Michael,Giovinazzo Jerome,Powell Brittany,Deobhakta Avnish,Wong Amanda,Zhu Daniel,Ferrone Philip J.,Gentile Ronald,Landa Gennady,Dayan Alan,Pollack Aryeh,Rosen Richard
Abstract
Background and Objective:
This study reports a case series of patients with persistent macular holes (MHs) who underwent human amniotic membrane subretinal placement to achieve successful anatomic MH closure.
Patients and Methods:
This was a retrospective case series of patients with persistently open full-thickness MHs who underwent human amniotic membrane placement. Patients were observed up to 6 months postoperatively.
Results:
Ten patients were included. The mean preoperative best-corrected visual acuity was 1.6 logMAR (20/800). Postoperatively, mean best-corrected visual acuity improved to 1.3 logMAR (20/400) at 1 month and 1.1 logMAR (20/250) by the 3- and 6-month visits. In all cases, the MH appeared closed at the 1-week visit and remained closed at their last follow-up. Optical coherence tomography showed closure in all cases. No adverse events were reported.
Conclusions:
Human amniotic membrane sub-retinal placement may serve as a useful surgical technique to assist in the closure of recalcitrant macular holes.
[
Ophthalmic Surg Lasers Imaging Retina
2023;54:218–222.]