Morphological Features of Full-Thickness Macular Holes Using Retromode Scanning Laser Ophthalmoscopy

Abstract

BACKGROUND AND OBJECTIVE: Retromode scanning laser ophthalmoscopy (RM-SLO) is a new imaging modality displaying pseudo-3D retinal images. We assessed the correlation between the morphological features of full-thickness macular holes (FTMHs) when using spectral domain–optical coherence tomography (SD-OCT) and when using RM-SLO. MATERIALS AND METHODS: This is a prospective observational case series in which patients were examined through SD-OCT and RM-SLO after informed consent was obtained. Intraclass correlation coefficient (ICC) and Pearson correlation coefficient (PCC) were used to assess interobserver agreement and the correlation between the diameters measured with the two techniques. RESULTS: We enrolled 20 patients (20 eyes) with an average hole aperture size of 426 μm (140–890 μm) on SD-OCT and 56 pixels (19–102 pixels) on RM-SLO. ICC and PCC were 0.999 and 0.992, respectively. “Standard” and “double-ring” FTMH patterns were described on RM-SLO and related well with SD-OCT findings. CONCLUSIONS: RM-SLO is a reliable method for FTMH-diameter evaluation and identifies unique pseudo-3D morphological features consistent with their B-scan counterparts. [ Ophthalmic Surg Lasers Imaging Retina 2022; 53:368–373.]