The two opposite facets of arsenic: toxic and anticancer drug

Author:

Florea Ana-Maria1,Büsselberg Dietrich2

Affiliation:

1. 1Universität Trier, Fachbereich VI Umwelttoxikologie, Universitätsring 15 54296 Trier, Germany

2. 2Weill Cornell Medical College in Qatar, Qatar Foundation – Education City, P.O. Box 24144, Doha, Qatar

Abstract

Arsenic compounds have been known and used for centuries but their effects in living organisms still represent a large unknown. Arsenic compounds have paradoxical effects: they are threatening to human health, especially upon long-term exposure that can induce the development of cancer; however, they are used as drugs against cancer. This review focuses on the effects shown by clinically and environmentally relevant arsenic compounds in living organisms with a focus on the calcium–apoptosis link.

Publisher

Hamad bin Khalifa University Press (HBKU Press)

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