Akut Pankreatitte Hemoglobin, Albümin, Lenfosit, Trombosit (HALP) Skorunun Rolü - Analitik Bir Çalışma

Abstract

Aim: The aim of this study is to assess the prognostic ability of Hemoglobin, Albumin, Lymphocyte, and Platelet parameters, as well as the calculated HALP score, in patients with acute pancreatitis. Additionally, it aimed to evaluate their association with prolonged hospitalization. Material and Methods: This analytical study was designed retrospectively. The study population consisted of patients diagnosed with acute pancreatitis who were followed up in the emergency department between the date of May 15, 2022, and January 31, 2023. Patients were categorized into two groups based on their 30-day mortality, namely survivors and non-survivors. Patients hospitalized for more than eight days were classified as prolonged hospitalizations. HALP score was calculated by using formula of hemoglobin(g/dL) × albumin(g/dL) × lymphocyte(103/µL) / platelet(103/µL). Comparisons between groups were conducted for the HALP score. Results: A total of 191 patients were included in the study. The rate of prolonged hospitalization was 23.6%. The mortality rate was 7.8%. The median HALP score was 3.1 (25th-75th percentiles: 2-5.4). There was no significant difference in the HALP score between survivors and non-survivors (3.2 (25th-75th percentiles: 2.1-5.4) versus 2.3 (25th-75th percentiles: 1.3-3.4), p = 0.050). However, there was a significant difference in the HALP score between the expected and prolonged hospitalization groups (3.4 (25th-75th percentiles: 2.1-5.7) versus 2.7 (25th-75th percentiles: 1.7-3.5), p=0.028). Conclusion: The HALP score may not contribute significantly to predicting mortality in patients with acute pancreatitis. Nevertheless, utilizing the HALP score to predict hospitalization duration can enhance the efficiency of healthcare providers in managing patients.