PRESENCE OF BRCA1 AND BRCA2 IN HEALTHY WOMEN AND MEN: DNA TESTING, DIAGNOSTIC ACTIVITIES AND CANCER PREVENTION
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Published:2017-02-01
Issue:2
Volume:63
Page:190-198
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ISSN:0507-3758
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Container-title:Problems in oncology
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language:
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Short-container-title:Problems in oncology
Author:
Imyanitov Yevgeniy,Belyaev Aleksey,Shcherbakov Aleksandr,Bershteyn Lev,Bessonov Aleksandr,Krivorotko Petr,Gorodnova Tatyana,Kotiv Khristina,Berlev Igor,Sokolenko Anna,Semiglazov Vladimir
Abstract
BRCA1 and BRCA2 germ-line mutations are associated in increased cancer risk both in women and in men. This article summarizes clinical recommendation of European Society for Medical Oncology (ESMO), National Comprehensive Cancer Network (NCCN) and other professional societies regarding inclusion criteria for BRCA-testing, diagnostic activities aimed to detect early cancers in BRCA1/2 mutation carriers as well as approaches to prevention of BRCA-driven cancers. The adjustment of existing clinical recommendations to health care realities in Russian Federation is discussed
Publisher
Autonomous non-profit scientific and medical organization - Questions of Oncology
Subject
Cancer Research,Oncology
Cited by
1 articles.
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