ANTIBACTERIAL PROPERTIES OF NEW BIOLOGICALLY ACTIVE SURGICAL SUTURES

Abstract

Objective: to evaluate the sorption potential of various antibiotics on polylactide and polypropylene surgical threads, whose surface is modified by direct radiation grafting of acrylic acid in the presence of N, N- methylene- bis- acrylamide, and antibacterial properties and capillarity of new surgical suture. Material and methods. The surface of the surgical sutures was modified by direct radiation grafting of acrylic acid. The bond strength of different antibacterial preparations was studied with modified threads. The antibacterial activity of the threads with Levofloxacin was studied against St.aureus, E.coli, Ps.aeruginosa . The capillarity of the modified surgical suture was studied. Results. The new surgical suture has a greater affinity to the fluoroquinolone antibiotics, has a pronounced antibacterial activity against E.coli, St.aureus, Ps.aeruginosa . Conclusion. The new surgical suture material can most effectively be used in surgery for prevention of infectious complications in the postoperative period.