MODERN PRINCIPLES OF CLASSIFICATION, PROGNOSIS AND TREATMENT OF PRIMARY MYELODYSPLASTIC SYNDROMES

Author:

Klimkovich N. N.1

Affiliation:

1. Belarusian Medical Academy of Post-Graduate Education

Abstract

Article is devoted myelodysplastic syndromes (MDS). It is group malignant diseases of a bone marrow in which basis the pathology hаemopoetic stem cells, leading to infringement proliferations and differentiations of hаemopoetic cells - predecessors with their change morphological and functional properties. Development of ordering MDS by variants, in particular, new classification the WHO (2008) is described. The estimation prognostic parametrs and systems is spent. Modern sights at treatment MDS with the account are presented an individualization of therapy on the basis of prognostic factors. The characteristic of new medical products and the analysis of results of application of standard therapeutic schemes in various modes and combinations is given.

Publisher

Gomel State Medical University

Reference28 articles.

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