INFLUENCE OF FORMALDEHYDE, DIBUTYL PHTHALATE, STYRENE AND THEIR COMBINATIONS ON ACTIVITY OF BIOPOWER PROCESSES OF RATS LIVER IN VITRO

Author:

Sobol Yu. A.1,Polovinkin L. V.1,Drozdova N. I.2

Affiliation:

1. Republican scientific-practical center of hygiene

2. Institute of biophysics and cellular engineering of a national academy of sciences of Byelorussia

Abstract

On utilised model of studying of respiratory activity of cells of a liver it is shown, that formaldehyde causes authentic activation of endogenic fabric respiration of cells of a liver, dibutyl phthalate (DBP) results in inhibition of respiration of mitochondrions, and styrene does not render significant influence on biopower processes of cells of a liver. In experiences in vitro it fixed, that formaldehyde and styrene in a combination causes activation of respiration of cells of a liver that is close to value of the specified index at isolated influence of formaldehyde. Entering of styrene and DBP causes activation of biopower processes of cells of a liver, and an admixture of formaldehyde and DBP - renders inhibiting influence on respiratory a chain of mitochondrions.

Publisher

Gomel State Medical University

Subject

General Medicine

Reference15 articles.

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