Affiliation:
1. Gomel State Medical University
2. Republican Research and Practical Centre for Medical Technologies, Informatization, Management and Economics of Public Health
Abstract
Objective. To identify the main demographic and clinical risk factors for the development of extrapulmonary tuberculosis (EPTB).Materials and methods. A retrospective study of tuberculosis cases registered from 2016 to 2020 in the Gomel region was conducted (330 patients with EPTB and 2,505 patients with pulmonary tuberculosis). The odds ratios were calculated to assess the risk factors for the development of EPTB.Results. The prevalence of EPTB was studied over the course of five years. The most significant risk factors for the development of tuberculosis in extrapulmonary localizations have been identified.Conclusion. The risk factors for the development of EPTB are age (EPTB often develops in children and older persons), females, and in those who have had an episode of tuberculosis previously. Awareness of the predisposing factors may help physicians maintain a high index of suspicion regarding the development of EPTB.
Publisher
Gomel State Medical University
Reference11 articles.
1. Global tuberculosis report 2020.[Electronic resource]. Geneva: World Health Organization 2020.Licence: CC BY-NC-SA 3.0 IGO. [date of access 2021 June 28]. Available from: https://apps.who.int/iris/bitstream/handle/10665/336069/9789240013131-eng.pdf
2. Pang Y, An J, Shu W, Huo F, Chu N, Gao M, et al. Epidemiology of Extrapulmonary Tuberculosis among Inpatients, China, 2008–2017. Emerg Infect Dis. 2019;25(3):457-464. DOI: https://doi.org/10.3201/eid2503.180572
3. Kang W, Yu J, Du J, Yang S, Chen H, Liu J, et al. The epidemiology of extrapulmonary tuberculosis in China: A large-scale multi-center observational study. PLoS One. 2020;15(8):e0237753. DOI: https://doi.org/10.1371/journal.pone.0237753
4. Sandgren A, Hollo V, van der Werf MJ. Extrapulmonary tuberculosis in the European Union and European Economic Area, 2002 to 2011. Euro Surveill. 2013;18(12):20431. DOI: https://doi.org/10.2807/ese.18.12.20431-en
5. Solonko II, Gurevich GL, Skryaginа EM, Dyusmikeevа MI. Extrapulmonary tuberculosis: clinical epidemiological characteristics and diagnostics. Tuberculosis and Lung Diseases. 2018;96(6):22-28. (In Russ.). DOI: https://doi.org/10.21292/2075-1230-2018-96-6-22-28