ASSOCIATION OF ANTIBODIES LEVEL TO CagA ANTIGEN OF Helicobacter pylori With HLA-antigens in duodenal ulcer patients-Reference-Cited by-同舟云学术

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ASSOCIATION OF ANTIBODIES LEVEL TO CagA ANTIGEN OF Helicobacter pylori With HLA-antigens in duodenal ulcer patients

Published:2007-03-28 Issue:1 Volume: Page:127-132
ISSN:2708-6011
Container-title:Health and Ecology Issues
language:
Short-container-title:jour

Author:

Shoot S. A.¹,Ugolnik T. S.¹,Levin V. I.²,Linkevich E. R.³,Konoplyanik N. V.¹,Stepanenko E. M.³

Affiliation:

1. Gomel State Medical University

2. Gomel Hemotransfusion Station

3. Republican Research Center of Hematology and Transfusiology

Abstract

Interconnection of serological reaction to CagA antigen of Helicobacter pylori in patients with duodenal ulcer and antigen of HLA-system has been examined. It was established that high antibodies titer to CagA antigen of Helicobacter pylori (IgG, IgA, IgM cumulative antibodies titer in blood serum of 1:80 and more) in patients with duodenal ulcer is associated with HLA-В7 antigen, HLA-А2,28 and В7,12 phenotypes and HLA-А1В15, А23В12 and А28В12 haplotypes.

Publisher

Gomel State Medical University

Subject

General Medicine

Reference15 articles.

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3. Immunogenetika i immunologiya: rezistentnost' k infektsii / R. M. Khaitov [i dr.]. - Tashkent: Izd-vo im. Ibn Siny, 1991. - 456 s.

4. Gotch, F. The major histocompatibility complex and disease / F. Gotch // Br. J. Biomed. Sci. -1996. - № 1. - R. 58-59.

5. Yazdovskii, V. V. Sistema HLA / V. V. Yazdovskii // Gemat. i transfuziol. - 1991. - № 7. - S. 30-35.

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