DYNAMICS OF BLOOD CORTISOL LEVELS IN ABDOMINAL AORTIC SURGERY IN CONDITIONS OF MULTICOMPONENT WELL-BALANCED ANESTHESIA

Abstract

Objective: to evaluate expression of stress hormonal response in reconstructive abdominal aortic surgery. Material and methods. The level of blood cortisol in patients operated for stenosing disorders and atherosclerotic aneurisms of the infrarenal aorta has been studied. Results. The patients recorded a statistically significant increase of the cortisol level during the stage of the clamping of the aorta - by 1.98 times in comparison with the preoperative one; during the stage of termination of the operation the level of blood serum cortisol did not show a statistically significant change and stayed to be increased by 1.79 times. Conclusion . The increase of the blood serum cortisol from 340.84 nmol/l at the admission of a patient into an operating theatre up to 676.19 nmol/l 3-5 minutes later after the clamping of the aorta and up to 613.51 nmol/l at the end of the operational intervention is a stress-norm in abdominal aortic surgery in conditions of multicomponent well-balanced anesthesia with application of propofol and fentanyl.