EXPERIMENTAL BASIS FOR THE APPLICATION OF ANTIOXIDANT «MEXIBEL» IN THE COPMLEX TRETMENT OF PYOINFLAMMATORY PROCESSES IN MAXILLOFACIAL AREA

Author:

Kabanova A. A.1,Bogdan N. Yu.1,Yarotzkaya N. N.2

Affiliation:

1. Belarusian State Medical University, Minsk

2. Vitebsk State Medical University

Abstract

The aim of the work was to study in experiment the effectiveness of antioxidant «Mexibel» for treatment for pyoinflammatory processes of maxillofacial area. 26 rabbits of Chinchilla breed were examined. The experiment consisted of three series: series of healthy animals (n = 10), control series (n = 8) - animals with submaxillary abscess, experimental series of rabbits treated with «Mexibel», dosage 9 mg/kg twice a day (n = 8). Lipid peroxidation, antioxidant activity, contents of dental conjugates were detected and examined in the blood serum. The findings allowed to make a conclusion about the effectiveness of the antioxidant «Mexibel» for the experimental animals with the model of a pyoinflammatory process in maxillofacial area and advisability to study its effects in the complex treatment for the maxillofacial area pyoinflammatory diseases of odontogenic etiology in clinical conditions.

Publisher

Gomel State Medical University

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