Design of Hammerhead Ribozymes that Cleave Murine Sry mRNA In Vitro and In Vivo

Author:

NAKAMURA Kaori1,MURATA Chisato1,ITO Masanori23,IWAMORI Tokuko13,NISHIMURA Seiichiro1,HISAMATSU Shin4,SONOKI Shigenori4,NAKAYAMA Aya2,SUYAMA Eigo25,KAWASAKI Hiroaki25,TAIRA Kazunari25,NISHINO Koichiro6,TACHI Chikashi127

Affiliation:

1. Laboratory of Develomental and Reproductive Biotechnology, Department of Animal Resource Sciences, School of Veterinary Medicine and Life Sciences, Azabu University

2. Gene Function Research Center, National Institute of Advanced Industrial Science and Technology

3. Laboratory of Applied Genetics, Department of Animal Resource Sciences, School of Agriculture and Life Sciences, The University of Tokyo

4. Laboratory of Environmental Chemistry, School of Environmental Health, Azabu University

5. Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo

6. Laboratory of Cellular Biochemistry, Department of Animal Resource Sciences, School of Agriculture and Life Sciences, The University of Tokyo

7. Mouse Genome Technology Center, Mitsubishi Kagaku Institute of Life Sciences

Publisher

Japanese Society of Animal Reproduction

Subject

Animal Science and Zoology

Reference28 articles.

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2. 2. Kawasaki H, Machida M, Komatsu M, Li HO, Murata T, Tsutsui H, Fujita A, Matsumura M, Kobayashi Y, Taira K, Yokoyama KK. Specific regulation of gene expression by antisense nucleic acids: a summary of methodologies and associated problems. Artif Organs 1996; 20: 836-848.

3. 3. Hampel A. Use of ribozymes to inhibit gene function. In: Proceedings of the 1998 Techniques in Reproductive Biology Workshop; 1998: Texas A & M University 601 Rudder Tower College Station, Texas. Hampel 1-12.

4. 4. Krupp G, Gaur RK (eds.). Ribozyme: Biochemistry and Biotechnology. Natick, MA: Eaton Publishing; 2000.

5. 5. Doherty EA, Doudna JA. Ribozyme structures and mechanisms. Annu Rev Biophys Biomol Struct 2001; 30: 457-475.

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