Abstract
We present a 47-year-old, South-African origin, woman with a background of stable monoclonal gammopathy of unknown significance (MGUS) who attended A&E with a history of coryzal symptoms associated with persistent fever, lymphadenopathy and a new onset of rash, not responding to antibiotics and paracetamol. A trial of high-dose steroids resolved symptoms. Bone marrow biopsy confirmed a progression of MGUS into multiple myeloma and her axillary lymph node biopsy analysis supported a diagnosis of Kikuchi-Fujimoto disease (KFD). This is an unusual presentation where KFD has been noted alongside MGUS progression to multiple myeloma. Haematology follow-up is underway.
Reference18 articles.
1. Kikuchi - Fujimoto disease;Satavahana Chowdary;Indian J Otolaryngol Head Neck Surg,2006
2. Celiac disease
3. Perry AM , Choi SM . The suggested pathogenesis of KFD is apoptosis driven by T-cell cytotoxicity via Fas and perforin pathways. In: Archives of pathology and laboratory medicine, 2018.
4. 2019 European League Against Rheumatism/American College of Rheumatology classification criteria for systemic lupus erythematosus
5. Development and validation of the HScore, a score for the diagnosis of reactive hemophagocytic syndrome;Fardet;Arthritis Rheumatol,2014
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献