Risk of second brain tumour after conservative surgery and radiotherapy for pituitary adenoma.

Author:

Brada M.,Ford D.,Ashley S.,Bliss J. M.,Crowley S.,Mason M.,Rajan B.,Traish D.

Publisher

BMJ

Subject

General Earth and Planetary Sciences,General Environmental Science,General Engineering

Reference20 articles.

1. Expected numbers of brain tumours, in total and by specific tumour type, were computed by using incidence rates in the South Thames region (available from the Thames Cancer Registry for 1961-88). Expected numbers of other second tumours were computed by using incidence rates for England and Wales (supplied by the Office of Population Censuses and Surveys; data available for 1971-84). In all analyses patients who had had a second tumour of a different type from the one under consideration were censored at the date of that tumour. All calculated p values are two sided and based on the Poisson distribution. The 95% confidence intervals for relative risk (observed to expected ratio) are exact;15

2. Radiotherapy of nonfunctional adenomas of the pituitary gland;Flickinger, J.C.; Nelson, P.B.; Martinez, A.J.; Deutsch, M.; Taylor, F.;Cancer,1989

3. Diagnosis and management of hormone-secreting pituitary adenomas;Klibanski, A.; Zervas, N.T.;N EnglJMed,1991

4. Results of transsphenoidal microsurgery for growth hormone-secreting pituitary adenoma in a series of 214 patients;Ross, D.A.; Wilson, C.B.;J Neurosurg,1988

5. Long-term results in transsphenoidal removal of nonfunctioning pituitary tumours;Ebersold, M.J.; Quast, L.M.; Laws, E.R.; Scheithauer, B.; Randall, R.V.;J Neurosurg,1986

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