Factor X deficiency and pregnancy

Author:

Chigateri Seema,Jain Apoorva,Oli Ajay Kumar,Katti Sathyasheelappa Sunil KumarORCID

Abstract

Factor X (FX) is a vitamin K-dependent enzyme, which acts as an important coagulation factor of coagulation cascade. FX deficiency is an autosomal recessive inherited disease and is often demonstrated in families with consanguity. Pregnancy in women with congenital FX deficiency has been associated with adverse fetal outcomes. We report a case of pregnancy in women with FX deficiency. The patient needed an immediate caesarean section at 38 weeks of gestation because of severe oligohydramnios and fetal distress. FX deficiency during pregnancy was effectively managed, leading to a positive outcome through the optimal utilisation of available resources.

Publisher

BMJ

Reference17 articles.

1. Factor X deficiency management for elective cesarean delivery in a pregnant patient;Krkovic;Am J Case Rep,2019

2. Congenital factor X deficiency in women: a systematic review of the literature;Spiliopoulos;Haemophilia,2019

3. Factor X deficiency and pregnancy: preconception counselling and therapeutic options;Nance;Haemophilia,2012

4. Severe factor X deficiency and successful pregnancy outcome: a rare case;Basu;J Appl Hematol,2018

5. Menorrhagia, and reproductive health in rare bleeding disorders: a study from the Indian subcontinent;Vijapurkar;Haemophilia,2009

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