Carcinoma en Cuirasse as the heralding sign of underlying HER-2 positive male breast cancer

Author:

Kapoor MayankORCID,Sundriyal DeepakORCID,Sehrawat Amit,Khanna Mridul

Abstract

Carcinoma en cuirasse (CeC) is an uncommon presentation of metastatic cutaneous carcinoma, most often originating from breast carcinoma. We present a case study of a man in his 30s exhibiting progressive skin thickening over the left chest, alongside appetite and weight loss. On examination, the patient had painless skin induration and palpable, matted, hard, immobile and non-tender axillary, cervical and inguinal lymphadenopathy. Imaging revealed metabolically active left cervical, retro pectoral, inguinal and bilateral axillary lymph nodes with muscle involvement, likely neoplastic. Histopathology demonstrated metastatic carcinoma, morphologically originating from the breast. CeC most often presents after therapy, but our case reveals that it may be a presenting sign of an occult malignancy. CeC should be differentiated from non-oncological causes of skin thickening. Detailed history, physical examination and appropriate radiological investigations are essential. Although rare in young individuals, neoplastic aetiology should be considered if the history and physical examination suggest it.

Publisher

BMJ

Reference9 articles.

1. Carcinoma en cuirasse;Ibrahim;JAMA Dermatol,2023

2. Male breast cancer in India: series from a cancer research centre;Sundriyal;Indian J Surg Oncol,2015

3. Male Breast Cancer: Epidemiology and Risk Factors

4. CANCER EN CUIRASSE

5. Rotational subtotal skin electron beam therapy for management of carcinoma en cuirasse;Kumar;J Natl Med Assoc,1987

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