Proceedings: Cell mediated immunity to synovial antigens in rheumatoid arthritis.

Author:

Bacon P A,Cracchiolo A,Bluestone R,Goldberg L S

Publisher

BMJ

Subject

General Biochemistry, Genetics and Molecular Biology,Immunology,Immunology and Allergy,Rheumatology

Reference11 articles.

1. Atlas of Standard Radiographs of Arthritis';KEELE, K.D.,1963

2. An unusual opportunity for such a study was provided by a total of 580 patient-weeks of chrysotherapy adjusted to individual 'tolerance', i.e. up to mild side-effects in everyone, in search of maximal efficacy,1973

3. Twenty-four patients with 'definite' or 'classical' RA, unresponsive to or intolerant of oral anti-inflammatory medication (including corticosteroids in 15) were treated. Clinical and laboratory parameters of inflammatory disease activity and of (potential) toxicity were monitored weekly, as well as 7th day serum gold levels (by atomic absorption against a weighed gold standard), as previously described in detail,1973

4. But at variance with a recent investigation (Co-operating clinics of;A, A.R.,1973

5. Our current hypothesis is that disturbances in the proportion of T cells in the peripheral blood and defects in T cell function pin-point defects in cellular immunity, sufficient to facilitate the spread of infective agents to the joints. This would account for the association of polyarthritis with the group characterized by anomalous T cell behaviour

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Biochemical analysis of synoviocytes from normal and arthritic rats. Evidence for an activated state associated with adjuvant polyarthritis;European Journal of Biochemistry;1987-01

2. References;Scandinavian Journal of Clinical and Laboratory Investigation;1978-01

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