Genetics of human blood coagulation.

Author:

Kerr C B

Publisher

BMJ

Subject

Genetics(clinical),Genetics

Reference465 articles.

1. Pitney and Elliot;Cooperberg; Teitlebaum;Egeberg and Owren; Rizza (I96i) Ingram,1960

2. Preston and Barr (1964), found a significant sex but not age effect;Pitney,1962

3. found neither;Kerr;Nilsson et al; found significantly higher levels in post-menopausal women. tRelative to blood group 0,1965

4. a normal curve (Fig. 6). Attempts to establish VIII synthesis at an X-linked and at least one a genetical component in variation are compromised autosomal locus (as discussed in section on von by undefined limits of non-genetical variability. Willebrand's disease);fits,1959

5. A remarkable number of environmental effects suggested that normal levels were controlled by influence factor VIII levels (Table VI). Many can autosomal genes. The question has been further be eliminated during planned investigation, but examined in two studies of factor VIII levels in others, notably 'anxiety' at venepuncture and errors members of normal families (Pitney et al., I962; inherent in assay techniques, remain an unknown Kerr;et al; Allowing as far as possible for source of variability,I965).

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