Renal Papillary Necrosis and Phenacetin: Two Further Cases

Author:

Kennedy A.

Publisher

BMJ

Subject

General Medicine

Reference27 articles.

1. Amelioration of Asthma and Hypertension after Nephrectomy for Renal Tuberculosis;MANOR, E.;J. Urol (Baltimore),1962

2. THE CONNECTION between phenacetin abuse and renal disease was postulated by Spuhler and Zollinger;Moolten and Smith; but reports of this association were confined to the Swiss and Scandinavian literature until 1960. The first case to be described in the United States was that of,1953

3. suggested that many cases, as yet unpublished. were known to American urologists. The findings of the European workers received substantial support from Australia in 1962 when Jacobs and Morris reported a study of 47 cases of renal papillary necrosis occurring in phenacetin takers; simultaneously, another six cases were published by McCutcheon,1962

4. No case of renal papillary necrosis due to phenacetin had been described in the United Kingdom until recently (Sanerkin and Weaver, 1964). The ensuing correspondence, in the British Medical Journal, revealed two more cases (Sanerkin, 1964; Jacobs, 1964) and a further case has been described by Scott,1964

5. This woman was admitted to hospital for the last time in November 1963 when she was aged 66 years. She had suffered from arthritis for 37 years and had received a course of gold injections when she was aged 40 years. At the age of 53 hysterectomy was performed for carcinoma of the body of the uterus. In 1952, when she was aged 56, it was noted that she was taking compound codeine tablets for the relief of her joint pains. In 1955 she had a course of treatment with phenylbutazone and in the following year a short course of steroid therapy was tried but

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