1. SORSBY, A. and UNGAR, J. (1946).-Brit. Med. Ji., ii, p. 723.
2. SORSBY, A. and UNGAR, J. (1948).-Brit. Ji. Ophthal. This issut, p. 857.
3. WHILST fhe experimental results recorded in the two preceding studies were being. established, a parallel investigation was conducted clinically to establish Whether, the eye tolerates subconjunctival injections. of more, than 50,000 units of crystalline penicillin and whether, the frequency of application could be reduced. The experimental result3 suggested that higher doses than 50,000 units have the two-fold advantage of giving a higher concentration of penicillin intra-ocularly and that this concentration persisted for longer than with the smaller doses. In an earlier study (Sorsby and Reed, 1947) dosage of 50,000 units of crystalline penicillin in adrenalin at six hourly [ntervals was advocated. The new experimental data suggested that with injections of 1,000,000 units in adrenalin the intervals might be prolonged to 48 hours
4. Two cases treated by injection of 100,000 units in 05 ml. at' 12 hourly intervals