1. The majority with abnormal IRT (22 of 26, 86%) had low concentrations while four (14%) had raised IRT concentrations. Whereas low IRT concentrations reflect a significantly diminished exocrine pancreatic reserve,2 3 the significance of raised IRT in serum is not clear. It has, however, been shown that in at least one other condition with chronic damage of exocrine pancreatic acinar tissue-cystic fibrosis-serum IRT can be raised without clinical evidence of acute pancreatitis.4 It is possible that Modell;I.R.T.,1975
2. Diagnostic importance of changes in circulating concentrations of immunoreactive trypsin;Elias, E.; Redshaw, M.; Wood, T.;Lancet,1977
3. Serum trypsin concentrations in diabetes mellitis;Dandona, P.; Elias, E.; Beckett, A.G.;Br MedJ,1978
4. Serum immunoreactive trypsin in cystic fibrosis;Dandona, P.; Hodson, M.E.; Bell, J.; Ramdial, L.; Beldon, I.; Batten, J.C.;Thorax,1981
5. Improvement in iron status and liver function with chronic subcutaneous desferrioxamine-therapy;Hoffbrand, A.V.; Gorman, A.; Laulicht, M.;Lancet,1979