V. Observations on the Lipoid Reinforcement of Antigens in the Gonococcal Complement Fixation Test

Author:

Messer A. I.,McLachlan A. E. W.

Publisher

BMJ

Subject

Infectious Diseases,Dermatology

Reference31 articles.

1. LORENZ, W. F. (1940), Amer. J. Clin. Path., 10, 527.

2. It is dismissed, for example, by Kolle and Hetsch,1934

3. as " of no value for diagnosis, for the methods at present in use do not give sufficiently reliable results." On the other hand Price,1933

4. introduced an antigen of a new type. This was intended primarily for use as a therapeutic vaccine. It is described as a "soluble gonotoxin" containing no killed or living gonococcal bodies, but only the " ectoand endo-toxins," and is apparently the fluid obtained by centrifuging a broth culture (the composition of this medium is not stated) in which gonococci have been grown to exhaustion, i.e., in effect a gonococcal " antivirus." This preparation was marketed in Germany under the name of " Compligon " and used as an antigen in gonococcal complement fixation tests. As such it has been the subject of favourable reports;Wolffenstein; Pieper,1931

5. Poehlmann, I935.)

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