Systematic review of high-dose amikacin regimens for the treatment of Gram-negative infections based on EUCAST dosing recommendations

Author:

Frost Kevin J,Hamilton Ryan AORCID,Hughes Stephen,Jamieson Conor,Rafferty Paul,Troise Oliver,Jenkins Abi

Publisher

BMJ

Subject

General Pharmacology, Toxicology and Pharmaceutics

Reference38 articles.

1. UK Health Security Agency . English surveillance programme for antimicrobial utilization and resistance (ESPAUR): report 2020 to 2021. Available: https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1033851/espaur-report-2020-to-2021-16-Nov.pdf [Accessed 20 Dec 2021].

2. Aminoglycoside Resistance

3. Treatment of infections caused by multidrug-resistant Gram-negative bacteria: report of the British Society for Antimicrobial Chemotherapy/Healthcare Infection Society/British Infection Association Joint Working Party†

4. Hospira UK Ltd . Summary of product characteristics: amikacin 250mg/5ml injection. Available: https://www.medicines.org.uk/emc/product/3784/smpc#gref [Accessed 20 Dec 2021].

5. European Committee on Antimicrobial Susceptibility Testing (EUCAST) . Amikacin: rationale for the EUCAST clinical breakpoints, version 2.0. Available: https://www.eucast.org/fileadmin/src/media/PDFs/EUCAST_files/Rationale_documents/Amikacin_rationale_1.2_0906.pdf [Accessed 20 Dec 2021].

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