1. The thymus in myasthenia gravis. Evidence for altered cell populations;Abdou, N.I.; Lisak, R.P.; Zweiman, B.; Abrahamsohn, I.; Penn, A.S.;N Engl; Med expected because in tumours, as a result of tissue hypoxia there is a shift in LDH isoenzyme pattern with prominence of M-subunit otherwise characteristic of anaerobic conditions.22 The predominance of LDH4 in the Hodgkin-type lymphoma structurally similar to foetal thymus23 tissue is not surprising, since this finding is generally characteristic of undifferentiated tissues such as tumours.24 On the other hand in the three other thymoma cases associated with minimal lymphocytic reactions no such alterations were seen. Even so, LDH isoenzyme pattern was shifted to the opposite direction; LDH2 alone was enhanced markedly with ensuing increment in H-subunit content. This type of change is however, characteristic of tissues with enhanced oxidative activities.25 In this particular tumour LDH isoenzyme composition is determined by the epithelial,1974
2. Immunological findings in thymic biopsies in myasthenia gravis: thymic immunohistology and mitogen reactivity;Christensson, B.; Biberfeld, P.; Matell, G.; Smith, C.I.E.; Hammarstrom, L.;Ann NY Acad Sci,1981
3. Thymic myogenesis, T-lymphocytes and the pathogenesis of myasthenia gravis;Wekerle, H.; Hohlfeld, R.;Ann NY Acad Sci,1981
4. Depletion of helper/inducer T cells after thymectomy in myasthenic patients;Berrih, S.; LeBrigand, H.; Ph, Levasseur; Gaud, C.; Bach, J.F.;Clin Immunol Immunopathol,1983
5. Acid esterase in human lymphoid cells and leukaemic blasts: a marker for T lymphocytes;Kulenkampff, J.; Janossy, G.; Greaves, M.F.;Br J Haematol; Terminal deoxynucleotidyl tranferase as a hematopoietic cell marker,1977