Benchmarking a universal smoking machine adaptor for tobacco product testing

Author:

El-Hellani AhmadORCID,Watson Clifford H,Huang Michelle,Wilson Clark W,Fleshman Clint C,Tran HangORCID,Chafin Dana,McGuigan Megan,Bravo Cardenas Roberto,Petitti Ryan,Pancake Mary,Bennett Chad,Mays DarrenORCID,Keller-Hamilton Brittney L,Jones Jeremy,Ye Wei,Schaff Jason,Borthwick Robert P,Williamson Raymond L,Wagener Theodore LORCID,Brinkman Marielle CORCID

Abstract

SignificanceCharacterisation of tobacco product emissions is an important step in assessing their impact on public health. Accurate and repeatable emissions data require that a leak-tight seal be made between the smoking or vaping machine and the mouth-end of the tobacco product being tested. This requirement is challenging because of the variety of tobacco product mouth-end geometries being puffed on by consumers today. We developed and tested a prototype universal smoking machine adaptor (USMA) that interfaces with existing machines and reliably seals with a variety of tobacco product masses and geometries.MethodsEmissions were machine-generated using the USMA and other available adaptors for a variety of electronic cigarettes (n=7 brands), cigars (n=4), cigarillos (n=2), a heated tobacco product, and a reference cigarette (1R6F), and mainstream total particulate matter (TPM) and nicotine were quantified. Data variability (precision, n≥10 replicates/brand) for all products and error (accuracy) from certified values (1R6F) were compared across adaptors.ResultsTPM and nicotine emissions generated using the USMA were accurate, precise and agreed with certified values for the 1R6F reference cigarette. Replicate data indicate that USMA repeatability across all tobacco products tested generally meets or exceeds that from the comparison adaptors and extant data.ConclusionThe USMA seals well with a variety of combustible tobacco products, e-cigarettes with differing geometries and plastic-tipped cigarillos. Variability for all measures was similar or smaller for the USMA compared with other adaptors.

Funder

Center for Tobacco Products

Publisher

BMJ

Reference40 articles.

1. FDA . FDA Authorizes Marketing of IQOS Tobacco Heating System with ‘Reduced Exposure’ Information, 2020. Available: https://www.fda.gov/news-events/press-announcements/fda-authorizes-marketing-iqos-tobacco-heating-system-reduced-exposure-information

2. A proposed cigarette emissions topography protocol reflecting Smokers’ natural environment use behavior;Hensel;PLoS One,2022

3. WHO . Information sheet on WHO TobLabNet methods for measuring priority contents and emissions in tobacco and related products. WHO/HEP/HPR/2020.1, 2020. Available: https://www.who.int/publications/i/item/WHO-HEP-HPR-2020.1

4. Smoking machine parameters and cigarette smoke yields;Darrall;Sci Total Environ,1988

5. “Comparison of mainstream smoke yields between linear and rotary smoking machines and evaluation of “super pad” extraction for linear smoking machines”;Liu;Chem Res Toxicol,2021

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