Exceptionally large, atypically located spindle cell lipoma

Author:

John MitchellORCID,Patel Shaan,Joseph George

Abstract

Spindle cell lipomas are a rare subtype of lipoma typically occurring in the shawl region of middle-aged men with a characteristic histological appearance consisting of mature adipocytes, ropey collagen and spindle cells. Those of extraordinary size or atypical anatomic location require a proper immunohistological workup to rule out more ominous malignancy. The authors report the rare presentation of a 54-year-old man with a large mass of the left palm causing discomfort and paresthesia for 6 months. Radiographs showed a radiolucent mass without mineralisation or bony involvement. MRI demonstrated a non-contrast-enhancing homogeneous lipomatous mass encompassing flexor tendons of the palm. Elective excisional biopsy and immunohistological analysis were consistent with spindle cell lipoma measuring 11 cm × 7 cm × 4 cm. This case is the largest spindle cell lipoma of the hand reported in the literature and appears to be the largest described in the upper extremity.

Publisher

BMJ

Subject

General Medicine

Reference11 articles.

1. Spindle cell lipoma;Enzinger;Cancer,1975

2. Updates in spindle cell/pleomorphic lipomas;Van Treeck;Semin Diagn Pathol,2019

3. An exceptionally large giant lipoma of the hand;Chatterton;BMJ Case Rep,2013

4. Spindle cell lipoma adherent to the digital nerve in the palm;Ciloglu;J Hand Microsurg,2014

5. Spindle cell lipoma of the hand;Mounasamy;European J Orthop Surg Traumatol,2006

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