Administration of a long-acting antipsychotic injection to a child while managing contraindicated polypharmacy interactions and transition between services

Author:

Akram GazalaORCID,Mitchell Fiona

Abstract

Second-generation antipsychotics are used to treat a variety of psychiatric symptoms and illnesses as well as the behavioural aspects of various neurodevelopmental disorders. However, there is reluctance in using second-generation long-acting injectable antipsychotics in child psychiatry services. We present a case of a 12-year-old child whose presentation and medication regime warranted the use of aripiprazole long-acting injection against a backdrop of potential CYP P450 enzyme interactions as a consequence of polypharmacy. The case also describes the difficulties encountered working across different health sectors and agencies and highlights the ongoing need for skills-based Continuous Professional Development for Child and Adolescent Mental Health Services-based nursing staff.

Publisher

BMJ

Subject

General Medicine

Reference5 articles.

1. Antipsychotic prescribing practice among child psychiatrists and community paediatricians;Otasowie;Psychiatrist,2010

2. The Role of Psychosocial Interventions in Bipolar II Disorder

3. Perceptions and knowledge of antipsychotics among mental health professionals and patients;Cahling;BJPsych Bull,2017

4. Weight Gain and Metabolic Risks Associated with Antipsychotic Medications in Children and Adolescents

5. Electronic Medicines compendium. Otsuka Pharmaceuticals, Abilify Maintena 400 mg powder and solvent for prolonged-release suspension for injection (Aripiprazole Summary of Product Characteristics). https://www.medicines.org.uk/emc/product/7965/smpc.

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