Acute myeloid leukaemia presenting as proptosis in an infant

Author:

Niazmand Mohammad Javad,Speckert Matthew,Johnston Donna

Abstract

Paediatric patients with acute myeloid leukaemia (AML) often present with symptoms associated with the disruption of normal haematopoiesis and subsequent cellular deficiencies. Periosteal reactions are common in paediatric leukaemia, but typically manifest as a thin, laminated pattern along long bones. Aggressive periosteal reactions are much less frequently seen. Here, we report a case of paediatric AML initially presenting with proptosis and periorbital swelling caused by aggressive, sunburst periosteal reactions surrounding the sphenoid and zygomatic bones. This unique presentation emphasises the importance of considering leukaemic infiltration in the differential for sunburst periosteal reaction in paediatric patients.

Publisher

BMJ

Subject

General Medicine

Reference14 articles.

1. Proptosis is a pediatric dilemma;Altonbary;Ann Pediatr Child Health,2015

2. Malignant childhood proptosis: study of 104 cases;Bakhshi;J Pediatr Hematol Oncol,2008

3. Goldenberg-Cohen N , Luckman J , Omary R . Primary tumors underlying unilateral orbital proptosis in children. Invest Ophthalmol Vis Sci 2017;58:2418 https://iovs.arvojournals.org/article.aspx?articleid=2640040

4. A clinical update and radiologic review of pediatric orbital and ocular tumors;Rao;J Oncol,2013

5. Orbital rhabdomyosarcomas: A review

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