Platypnoea-orthodeoxia syndrome: the importance of the patient’s posture for diagnosis

Author:

Fontes Carla PereiraORCID,Fonseca Samuel Barbosa,Santos Mário

Abstract

Platypnoea-orthodeoxia syndrome (POS) is a rare condition characterised by the association of dyspnoea and arterial oxygen desaturation induced by standing and relieved by recumbency. The precise mechanism remains poorly understood, but it appears to involve both anatomical and functional components producing a significant right-to-left shunting under certain postural conditions. This syndrome is associated with either intracardiac or extracardiac aetiologies, and the diagnosis depends on high clinical suspicion. Intracardiac shunt is the most common cause of POS and can be identified through echocardiography with bubble study. We report the case of a patient with POS secondary to a paradoxical shunt through the patent foramen oval, whose definitive diagnosis was only possible with contrasted transthoracic echocardiography in the sitting and standing positions.

Publisher

BMJ

Subject

General Medicine

Reference15 articles.

1. Reproducibility of values for oxygen saturation of arterial blood, and magnitude of venous-arterial shunts in patients with congenital cardiac malformations;Burchell;J Appl Physiol,1949

2. Treatment of Platypnea-Orthodeoxia syndrome in a patient with normal cardiac hemodynamics: a review of mechanisms with implications for management;Porter;Methodist Debakey Cardiovasc J,2018

3. Biphasic Effects of Statins on Angiogenesis

4. The multiple dimensions of Platypnea-Orthodeoxia syndrome: a review;Agrawal;Respir Med,2017

5. Platypnea-orthodeoxia syndrome: Etiology, differential diagnosis, and management

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