Author:
Murphy Treasa,Raheem Abu Shanab Abdul,Kang Kristopher,Lyons Christopher J
Abstract
A 14-year-old boy was referred to the ophthalmology department with a 4-day history of rapid-onset right upper lid pain, swelling and erythema starting 9 hours after his first dose of COVID-19 mRNA vaccination (BNT162b2/Comirnaty, Pfizer-BioNTech). On examination, he had significant right upper lid ptosis, oedema and erythema, with associated limitation of right eye abduction and elevation. He was found to have acute dacryoadenitis with orbital inflammatory disease on clinical and laboratory investigations. He was given tapering oral prednisone and had full resolution of symptoms within 2 weeks. This is the first known case of orbital inflammation after COVID-19 mRNA vaccination. Given the temporal association between the patient’s vaccination and symptom onset, we believe it is likely that immunisation prompted the onset of disease.
Reference18 articles.
1. Unique characteristics of lacrimal glands as a part of mucosal immune network: high frequency of IgA-committed B-1 cells and NK1.1+ alphabeta T cells;Saitoh-Inagawa;Invest Ophthalmol Vis Sci,2000
2. Acute dacryoadenitis in a patient with SARS-CoV-2 infection;Martínez Díaz;Orbit,2021
3. The role of the ocular tissue in SARS-CoV-2 transmission;Peng;Clin Ophthalmol,2020
4. Episcleritis as a possible presenting sign of the novel coronavirus disease: a case report;Otaif;Am J Ophthalmol Case Rep,2020
5. Anterior acute uveitis report in a SARS-CoV-2 patient managed with adjunctive topical antiseptic prophylaxis preventing 2019-nCoV spread through the ocular surface route;Mazzotta;Int Med Case Rep J,2020
Cited by
11 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献