Abstract
Giant fornix syndrome (GFS) results in chronic, relapsing conjunctivitis in elderly patients with enophthalmos and enlarged fornices, in which infectious material collects and perpetuates inflammation. A 98-year-old woman presented with persistent, bilateral, purulent conjunctivitis; corneal epithelial defects and progressive blepharospasm that did not respond to artificial tears, topical antibiotics and steroids and amniotic membrane grafts. Additional findings of deep-set orbits with enlarged upper fornices were diagnostic of GFS. Over the next 2 months, she responded to a combination of topical and systemic antibiotics, autologous serum eye drops, povidone-iodine forniceal rinses, and hypochlorous acid treatment of the eyelashes. GFS is an important diagnostic consideration in elderly patients with chronic conjunctivitis and deep-set orbits.
Reference19 articles.
1. Giant fornix syndrome with chronic methicillin resistant staphylococcus aureus conjunctivitis causing nasal lacrimal duct obstruction [abstract];Lever;Invest Ophthalmol Vis Sci,2013
2. Giant fornix syndrome;Mokete;Ophthalmology,2005
3. The giant fornix syndrome
4. Conjunctivitis preferred practice Pattern®;Varu;Ophthalmology,2019
5. Giant fornix syndrome: a recently described cause of chronic purulent conjunctivitis and severe ocular surface inflammation, with a new diagnostic sign on CT;Turner;Eye,2006