Surgical congenital anomalies in Albania: incidence, prenatal diagnosis and outcome
-
Published:2019-02
Issue:1
Volume:2
Page:e000012
-
ISSN:2516-5410
-
Container-title:World Journal of Pediatric Surgery
-
language:en
-
Short-container-title:World Jnl Ped Surgery
Author:
Bakalli Ilirjana,Kola Elmira,Lluka Robert,Celaj Ermela,Sala Durim,Gjeta Inva,Sallabanda Sashenka,Klironomi Dea
Abstract
IntroductionSignificant progress has been made in the diagnosis and management of congenital anomalies (CA). In our study, we aimed to evaluate prenatal diagnosis, trend of surgical CA, mortality rate and the factors affecting their prognosis in our country.MethodsWe enrolled in our study all children with CA who underwent surgery from January 2008 to December 2017. We compared prenatal diagnosis, incidence and mortality for two 5-year periods: the first period in 2008–2012 and the second period in 2013–2017.ResultsDuring the study period, a total of 321 cases with CA were presented, with an incidence of 0.69–1.18 per 1000 live births. Intestinal, anal and esophageal atresia remain the most important CAs (23%, 18% and 16%), followed by diaphragmatic hernia and gastroschisis (10% and 7%). Comparing the incidence for the two periods, we did not find statistical differences (p=0.73), but the mortality rate has been reduced from 31.4% during the first period to 24.6% during the second period (p=0.17). Prenatal diagnosis has increased: 28% in the second period compared with 10% in the first period (p<0.001), without significantly affecting the prognosis (p=0.09). Birth of premature babies resulted in a significantly negative predictive factor for the prognosis of these anomalies (p=0.0002).ConclusionIncidence of CA has not changed over the years in our country. Advances in intensive care, surgical techniques and parenteral nutrition made in recent years have significantly increased the survival of neonates born with surgical CA. Birth of premature babies was a significantly negative predictive factor for the prognosis of these anomalies.
Subject
Pediatrics, Perinatology and Child Health,Surgery
Reference45 articles.
1. Birth defects . Data&Statistics. CDC. Available: https://www.cdc.gov/ncbddd/birthdefects/data.html
2. Birth defects – report by the Secretariat , 2009. Available: http://apps.who.int/iris/handle/10665/2271
3. Congenital anomalies , 2016. Available: http://www.who.int/news-room/fact-sheets/detail/congenital-anomalies
4. Birth defects surveillance: atlas of selected anomalies. Available: http://www.who.int/nutrition/publications/birthdefects_atlas/en/
5. Prenatal diagnosis , 2013. Available: https://library.med.utah.edu/WebPath/TUTORIAL/PRENATAL/PRENATAL.html
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献