Chronic airflow obstruction and ambient particulate air pollution

Author:

Amaral Andre F SORCID,Burney Peter G J,Patel Jaymini,Minelli CosettaORCID,Mejza FilipORCID,Mannino David M,Seemungal Terence A R,Mahesh Padukudru AnandORCID,Lo Li Cher,Janson ChristerORCID,Juvekar Sanjay,Denguezli Meriam,Harrabi Imed,Wouters Emiel F M,Cherkaski Hamid,Mortimer KevinORCID,Jogi Rain,Bateman Eric D,Fuertes ElaineORCID,Al Ghobain Mohammed,Tan Wan,Obaseki Daniel O,El Sony Asma,Studnicka Michael,Aquart-Stewart Althea,Koul Parvaiz,Lawin Herve,Nafees Asaad Ahmed,Awopeju Olayemi,Erhabor Gregory E,Gislason Thorarinn,Welte Tobias,Gulsvik Amund,Nielsen Rune,Gnatiuc Louisa,Kocabas Ali,Marks Guy BORCID,Sooronbaev Talant,Mbatchou Ngahane Bertrand Hugo,Barbara Cristina,Buist A Sonia

Abstract

Smoking is the most well-established cause of chronic airflow obstruction (CAO) but particulate air pollution and poverty have also been implicated. We regressed sex-specific prevalence of CAO from 41 Burden of Obstructive Lung Disease study sites against smoking prevalence from the same study, the gross national income per capita and the local annual mean level of ambient particulate matter (PM2.5) using negative binomial regression. The prevalence of CAO was not independently associated with PM2.5 but was strongly associated with smoking and was also associated with poverty. Strengthening tobacco control and improved understanding of the link between CAO and poverty should be prioritised.

Funder

Wellcome Trust

Publisher

BMJ

Subject

Pulmonary and Respiratory Medicine

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