Joint patient and clinician priority setting to identify 10 key research questions regarding the long-term sequelae of COVID-19

Author:

Houchen-Wolloff Linzy,Poinasamy Krisnah,Holmes Kate,Tarpey Maryrose,Hastie Claire,Raihani Kelly,Rogers Natalie,Smith Nikki,Adams Dawn,Burgess Paul,Clark Jean,Cranage Clare,Desai Mahadev,Geary Nicola,Gill Rhyan,Mangwani Jitendra,Staunton Lily,Berry Colin,Bolton Charlotte EORCID,Chalder Trudie,Chalmers James,De Soyza Anthony,Elneima OmerORCID,Geddes John,Heller Simon,Ho Ling-Pei,Jacob Joseph,McAuley Hamish,Parmar Aarti,Quint Jennifer KORCID,Raman Betty,Rowland Matthew,Singapuri Amisha,Singh Sally J,Thomas David,Toshner Mark RORCID,Wain Louise V,Horsley Alex RobertORCID,Marks Michael,Brightling Christopher EORCID,Evans Rachael AORCID

Abstract

Given the large numbers of people infected and high rates of ongoing morbidity, research is clearly required to address the needs of adult survivors of COVID-19 living with ongoing symptoms (long COVID). To help direct resource and research efforts, we completed a research prioritisation process incorporating views from adults with ongoing symptoms of COVID-19, carers, clinicians and clinical researchers. The final top 10 research questions were agreed at an independently mediated workshop and included: identifying underlying mechanisms of long COVID, establishing diagnostic tools, understanding trajectory of recovery and evaluating the role of interventions both during the acute and persistent phases of the illness.

Funder

National Institute for Health Research

Publisher

BMJ

Subject

Pulmonary and Respiratory Medicine

Reference10 articles.

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4. Evans RA , Leavy OC , Richardson M , on behalf of the PHOSP-COVID Collaborative Group . Clinical characteristics with inflammation profiling of Long-COVID and association with one-year recovery following hospitalisation in the UK: a prospective observational study. medRxiv 2021.doi:10.1101/2021.12.13.21267471

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