Leber's hereditary optic neuropathy: heteroplasmy is likely to be significant in the expression of LHON in families with the 3460 ND1 mutation.

Author:

Black G C,Morten K,Laborde A,Poulton J

Publisher

BMJ

Subject

Cellular and Molecular Neuroscience,Sensory Systems,Ophthalmology

Reference11 articles.

1. A new mtDNA mutation associated with Leber hereditary optic neuroretinopathy;Huoponen, K.; Vilkki, J.; Aula, P.; Nikoskelainen, E.K.; Savontaus, M.-L.;Am J7 Hum Genet,1991

2. Leber hereditary optic neuropathy: identification of the same mitochondrial ND1 mutation in six pedigrees;Howell, N.; Bindoff, L.A.; McCullough, D.A.; Kubacka, I.; Poulton, J.; Mackey, D.;Am J Hum Genet,1991

3. Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy;Wallace, D.C.; Singh, G.; Lott, M.T.; Hodge, J.A.; Schurr, T.G.; Lezza, A.M.S.;Science,1988

4. A variant of Leber hereditary optic neuropathy characterized by recovery of vision and by an unusual mitochondrial genetic etiology;Mackey, D.; Howell, N.;Am Y Hum Genet,1992

5. When does bilateral optic atrophy become Leber hereditary optic neuropathy?;Howell, N.; Halvorson, S.; Burns, J.; McCullough, D.A.; Poulton, J.;Am J Hum Genet,1993

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