BET 2: Is the use of long-acting neuromuscular blocking agents for intubation associated with reduced provision of postintubation sedation?

Author:

Buswell Luke,Hayes Alastair

Abstract

A short cut review was conducted to assess if the use of rocuronium in the ED was associated with a decrease in the provision of postintubation sedation. Four papers were identified that presented the best evidence to answer the question. Again the studies, relevant outcomes, results and weaknesses are tabulated. All the identified studies were retrospective and there was a plethora of outcome measures used. When compared with suxamethonium, rocuronium was associated with a delayed initiation and reduced dose of postintubation sedation.

Publisher

BMJ

Subject

Critical Care and Intensive Care Medicine,General Medicine,Emergency Medicine

Reference9 articles.

1. Medicines.org.uk . Rocuronium bromide: SmPC, 2019. Available: https://www.medicines.org.uk/emc/product/1345/smpc [Accessed Jun 2019].

2. Medicines.org.uk . Suxamethonium chloride: SmPC, 2019. Available: https://www.medicines.org.uk/emc/product/5189/smpc [Accessed Jun 2019].

3. Awareness During Anesthesia: Risk Factors, Causes and Sequelae: A Review of Reported Cases in the Literature

4. Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU

5. Rocuronium versus suxamethonium: a survey of first-line muscle relaxant use in UK prehospital rapid sequence induction;Hartley;Prehosp Disaster Med,2015

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