1. The present technique offers several advantages over mixed leucocyte preparations. A granulocyte preparation allows the dosage of radioactivity to be reduced by up to half by avoiding Hodgson HJF. Assessment of drug therapy in inflammatory bowel disease;Br J Clin Pharmacol,1982
2. Radiographic unwanted red cell, lymphocyte, and platelet contamination, which increases background to target organ activity. Use of "'In tropolonate to label granulocytes in plasma permits rapid visualisation of inflammatory sites,'3 with accurate localisation findings of the National Co-operative Crohn's Disease Study;Goldberg, H.I.; Caruthers, S.B.; Nelson, J.A.; Singleton, J.W.;Gastroenterology,1979
3. A comparative study of metronidazole and sulfasalazine for active Crohn's disease: the co-operative Crohn's disease study in Sweden. Gastroenterology 1982; 83: 550-62. within three hours after reinjection rather than the 16-24 hours used by other workers.'2 14 In addition to shortening the time for investigation early scanning avoids the errors in determining disease distribution consequent on delayed scanning;Ursing, B.O.; Alm, T.; Barany, F.
4. Cortisone in ulcerative colitis: final report on a therapeutic trial;Truelove, S.; Witts, L.J.;Br MedJ,1955
5. Microscopic colitis-a cause of chronic watery diarrhoea. Br MedJ7;Kingham, J.G.; Levison, D.A.; Bell, J.A.; Dawson, A.M.;Lancet; Colonoscopic diagnosis intraluminal transit of activity has occurred. A major difficulty in evaluating a new assessment of disease activity in inflammatory bowel disease is the lack of an accepted "gold standard." The Crohn's disease activity index is useful of minimal change colitis in patients with a normal sigmoidoscopy and normal air-contrast barium enema,1982