Fluctuations in anti-nRNP levels in patients with mixed connective tissue disease are related to disease activity as part of a polyclonal B cell response.

Author:

Houtman P M,Kallenberg C G,Limburg P C,van Leeuwen M A,van Rijswijk M H,The T H

Publisher

BMJ

Subject

General Biochemistry, Genetics and Molecular Biology,Immunology,Immunology and Allergy,Rheumatology

Reference19 articles.

1. Mixed connective tissue discasc-an apparcntls distinct rheumatic disease syndrome associated with a spccific antibods to an extractable nuclear antigen (ENA);R, Sharp G.C.Irvin W.A.Tan E.M.Gould R.G.Holman H.;Ami J Med,1972

2. Problems in differentiating SLE and mixed connective tissue disease;Reichlin, M.;N Engl J Med,1976

3. Mixed connectivc tissuc discasc syndrome: the cutaneous manifestations of patients with high titer serum antibody to RNase sensitivc cxtractable nuclear antigen (ENA);N, Gilliam J.; D, Prystowsky S.;Arch Dermatol,1977

4. Antibody to nuclear ribonucleoprotein penetrates live human mononuclear cells through Fc-receptors;Alarcon-Segovia, D.; Fishbein, Ruiz Arguelles A.; E.;Nature,1978

5. Observations on the in vivo reaction of antinuclear antibodies with epidermal cells;T, Izuno G.;Br J Der, natol,1978

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