Level of education is associated with coronary heart disease and chronic kidney disease in individuals with type 2 diabetes: a population-based study

Author:

Slåtsve Kristina B,Claudi Tor,Lappegård Knut Tore,Jenum Anne KarenORCID,Larsen Marthe,Nøkleby Kjersti,Tibballs KatrinaORCID,Cooper John G,Sandberg Sverre,Buhl Esben Selmer,Løvaas Karianne Fjeld,Berg Tore Julsrud

Abstract

IntroductionTo study the relationship between education level and vascular complications in individuals with type 2 diabetes in Norway.Research design and methodsMultiregional population-based cross-sectional study of individuals with type 2 diabetes in primary care. Data were extracted from electronic medical records in the period 2012–2014. Information on education level was obtained from Statistics Norway. Using multivariable multilevel regression analyses on imputed data we analyzed the association between education level and vascular complications. We adjusted for age, sex, HbA1c, low-density lipoprotein cholesterol, systolic blood pressure, smoking and diabetes duration. Results are presented as ORs and 95% CIs.ResultsOf 8192 individuals with type 2 diabetes included, 34.0% had completed compulsory education, 49.0% upper secondary education and 16.9% higher education. The prevalence of vascular complications in the three education groups was: coronary heart disease 25.9%, 23.0% and 16.9%; stroke 9.6%, 7.4% and 6.6%; chronic kidney disease (estimated glomerular filtration rate <60 mL/min/1.73 m2) 23.9%, 16.8% and 12.6%; and retinopathy 13.9%, 11.5% and 11.7%, respectively. Higher education was associated with lower odds for coronary heart disease (OR 0.59; 95% CI 0.49 to 0.71) and chronic kidney disease (OR 0.75; 95% CI 0.60 to 0.93) compared with compulsory education when adjusting for age, sex, HbA1c, low-density lipoprotein cholesterol, systolic blood pressure, smoking and diabetes duration.ConclusionsIn a country with equal access to healthcare, high education level was associated with lower odds for coronary heart disease and chronic kidney disease in individuals with type 2 diabetes.

Funder

Northern Norway Regional Health Authority

Norwegian Diabetes Association

Regional Health Authority, the Endocrinology Research Foundation, Stavanger

University of Oslo

AstraZeneca, Boehringer Ingelheim, Eli Lilly, MSD, Novo Nordisk, Sanofi Aventis

Publisher

BMJ

Subject

Endocrinology, Diabetes and Metabolism

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