1. Annals of the Rhewnatic Diseases daily. The mean plasma level of uric acid in the significantly reduced renal clearance of uric acid present group of gouty patients (7'9 mg./100 ml.) in the gouty subjects (3 6 ml./min.) compared with is lower;than the; ml. given in the study the controls (5 8 ml./min.), indicating that factors of Gutman and Yu,1957