Normative value of hyperopia reserve and myopic shift in Chinese children and adolescents aged 3–16 years

Author:

Wang JingjingORCID,Qi ZiyiORCID,Feng Yanqing,Chen Jun,Du Linlin,Yang JinliuxingORCID,Xie Hui,Zhu JianfengORCID,Zou Haidong,He XianguiORCID,Xu XunORCID

Abstract

BackgroundThis research aims to generate normative values of hyperopia reserve and refractive progression as effective tools to estimate the risk of myopia.MethodsA 1-year follow-up study was conducted among Chinese children and adolescents aged 3–16 years selected from schools and kinder gardens using cluster sampling. All participants underwent examinations including visual acuity, axial length and cycloplegic autorefraction (1% cyclopentolate). Percentiles of spherical equivalent (SE) were calculated using Lambda-Mu-Sigma (LMS) method. Age-specific refractive progression and hyperopia reserve were determined by backward calculation.ResultsOf 3118 participants, 1702 (54.6%) were boys with a mean baseline age of 7.30 years. The 50th percentile of SE estimated by LMS decreased from 1.04 D at 3 years to −2.04 D at 16 years in boys, while from 1.29 D to −2.81 D in girls. The 1-year refractive progression of myopes (0.81 D) was greater than that of non-myopes (0.51 D). The normative value of hyperopia reserve was 2.64 (range: 2.40 D–2.88 D) at 3 years and −0.35 (range: −0.50 to −0.17) D at 16 years, with the maximum progression of 0.35 D at the age of 6 years.ConclusionAge-specific normative values of hyperopia reserve and yearly myopic shift in children and adolescents aged 3–16 years were provided, helping identify and monitor myopia and giving prevention in advance.

Funder

National Key R&D Program of the Ministry of science and technology

Shanghai Hospital Development Center Management Project

National Natural Science Foundation of China

Excellent Discipline Leader Cultivation Program of Shanghai Three Year Action Plan on Strengthening Public Health System Construction

National Key R&D Program

Project of Shanghai Health Commission

Publisher

BMJ

Subject

Cellular and Molecular Neuroscience,Sensory Systems,Ophthalmology

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