1. age/sex specific rates only 0-9
2. Rising rate from 1952 and then a fall after 1960. Includes worldwide mortality data 1954-1971 compared with Parkinson's disease which did not change Increasing mortality over study period. Standardised mortality ratio 79 in 1968, 129 in 1986. Non random distribution in place Figures divided into ALS and MND as a whole. Rise greater for ALS. Age standardised rate doubled over study period. Rising rates, with substantial changes particularly amongst the elderly More common in women,>55
3. 1925-84 Mayo clinic computerised Y Y;Rochester
4. Italy 1965-74;Sardinia
5. North Sweden 1969-80 Neurology department, Y N N 0-65 questionnaire to others, Death certificates Varmland 1970-81 Inquiry to clinics of