Mechanism of action of intradiscal chymopapain in the treatment of sciatica: a clinical, biochemical, and radiological study.

Author:

Jenner J R,Buttle D J,Dixon A K

Publisher

BMJ

Subject

General Biochemistry, Genetics and Molecular Biology,Immunology,Immunology and Allergy,Rheumatology

Reference33 articles.

1. Chymopapain for the treatment of intervertebral disc herniation. A preliminary report of a double-blind study;D, Fraser R.;Spine,1982

2. and efficacy of chymopapain (Chymodiactin) in herniated nucleus pulposus with sciatica. Results of a randomised double-blind study;J, Javid M.;JAMA,1983

3. A comparison of surgery and chemonucleolysis in the treatment of sciatica;M, Crawshaw C.Frazer A.; C, Merriman W.F.Mulholland R.; K, Webb J.;Spine,1984

4. Treatment of lumbar intervertebral disc lesions by direct injection of chymopapain;Smith, L.; E, Brown J.;J Bone Joint Surg,1967

5. Effect of x-ray contrast media on the action of chymopapain on the intervertebral disc: an in vitro study of cartilage degradation;J, Buttle D.; J, Tudor; J, Barrett A.;Br J Radiol

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