Saliva carbamazepine and phenytoin level monitoring.

Author:

Rylance G W,Moreland T A

Publisher

BMJ

Subject

Pediatrics, Perinatology and Child Health

Reference6 articles.

1. Drug level monitoring in paediatric practice;W, Rylance G.; A, Moreland T.;Arch Dis Child,1980

2. Use of saliva in monitoring carbamazepine medication in epileptic or to dose-dependent autoinduction of CBZ metachildren. Eur JPediatr 1977; 126: 37-44. bolism. The elimination ofDPH by both first and zero order kinetics may partly explain why there is a poor relationship between its dose and saliva level;Bartels, H.; Oldigs, H.-D.; Gunther, E.

3. Phenytoin and phenobarbital concentrations in saliva and plasma measured by radioimmunoassay;E, Cook C.; E, Amerson; K, Poole W.; P, Lesser; L, O.'Tuama;Clin Pharmacol Ther,1975

4. Therapeutic monitoring of anticonvulsant drugs: gas chromatographic level was evident, particularly between dose and the simultaneous determination of primidone, phenylethyl- 3-and 5-hour post-dose levels. The good relationship between dose and the 3-and 5-hour post-dose levels may reflect diminishing saliva contamination malonamide, carbamazepine, and diphenylhydantoin;Least C J, Jr, Johnson G.F.; M, Solomon H.;Clin Chem,1975

5. Pharmacokinetics of a single dose of phenytoin in man with time from dosing, or it may suggest that levels measured by radioimmunoassay. Br J Clin Pharmacol in the elimination phase are better related to the dose than those at the time of absorption. The good correlation between the dose and the 5-hour sample;D, Robinson J.; A, Morris B.; W, Aherne G.; V, Marks,1975

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