Development and validation of the Fracture Risk Scale (FRS) that predicts fracture over a 1-year time period in institutionalised frail older people living in Canada: an electronic record-linked longitudinal cohort study

Author:

Ioannidis George,Jantzi Micaela,Bucek Jenn,Adachi Jonathan D,Giangregorio Lora,Hirdes John,Pickard Laura,Papaioannou Alexandra

Abstract

ObjectivesTo develop and validate our Fracture Risk Scale (FRS) over a 1-year time period, using the long-term care (LTC) Resident Assessment Instrument Minimum Data Set Version 2.0 (RAI-MDS 2.0).DesignA retrospective cohort study.SettingLTC homes in Ontario, Canada.ParticipantsOlder adults who were admitted to LTC and received a RAI-MDS 2.0 admission assessment between 2006 and 2010.ResultsA total of 29 848 LTC residents were enrolled in the study. Of these 22 386 were included in the derivation dataset and 7462 individual were included in the validation dataset. Approximately 2/3 of the entire sample were women and 45% were 85 years of age or older. A total of 1553 (5.2%) fractures were reported over the 1-year time period. Of these, 959 (61.8%) were hip fractures. Following a hip fracture, 6.3% of individuals died in the emergency department or as an inpatient admission and did not return to their LTC home. Using decision tree analysis, our final outcome scale had eight risk levels of differentiation. The percentage of individuals with a hip fracture ranged from 0.6% (lowest risk level) to 12.6% (highest risk level). The area under the curve of the outcome scale was similar for the derivation (0.67) and validation (0.69) samples, and the scale exhibited a good level of consistency.ConclusionsOur FRS predicts hip fracture over a 1-year time period and should be used as an aid to support clinical decisions in the care planning of LTC residents. Future research should focus on the transformation of our scale to a Clinical Assessment Protocol and to assess the FRS in other healthcare settings.

Funder

The Ministry of Health and Long-Term care through the Ontario Osteoporosis Strategy for Long-Term Care

Publisher

BMJ

Subject

General Medicine

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